KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
13.64
Human Site:
Y345
Identified Species:
30
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
Y345
T
M
V
P
P
G
V
Y
M
R
N
A
S
C
H
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
Y344
T
M
V
P
P
G
V
Y
M
R
N
A
S
C
H
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
E279
Q
H
P
D
W
G
D
E
E
L
F
Q
H
A
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
Y345
T
M
V
P
P
G
V
Y
M
R
N
S
S
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
Y345
T
M
V
P
S
G
V
Y
M
R
D
A
S
C
H
Chicken
Gallus gallus
XP_425053
1523
173782
G324
L
A
T
T
V
P
P
G
V
Y
K
R
D
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
A224
Y
E
F
G
N
A
W
A
N
E
N
I
F
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
M311
A
F
R
F
G
H
T
M
I
P
P
G
I
Y
R
Honey Bee
Apis mellifera
XP_624355
1492
172466
L325
A
F
R
F
G
H
T
L
I
P
P
G
L
Y
R
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
P334
R
F
P
H
S
I
V
P
P
A
M
L
L
R
K
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
T443
N
E
Q
C
V
F
R
T
S
T
M
K
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
100
6.6
N.A.
N.A.
N.A.
93.3
N.A.
86.6
0
N.A.
6.6
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
6.6
N.A.
N.A.
N.A.
100
N.A.
93.3
6.6
N.A.
6.6
N.A.
6.6
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
10
0
10
0
10
0
28
0
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
37
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
0
10
0
10
0
0
% D
% Glu:
0
19
0
0
0
0
0
10
10
10
0
0
0
0
0
% E
% Phe:
0
28
10
19
0
10
0
0
0
0
10
0
10
0
0
% F
% Gly:
0
0
0
10
19
46
0
10
0
0
0
19
0
0
10
% G
% His:
0
10
0
10
0
19
0
0
0
0
0
0
10
0
37
% H
% Ile:
0
0
0
0
0
10
0
0
19
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
10
0
10
0
10
19
0
0
% L
% Met:
0
37
0
0
0
0
0
10
37
0
19
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
10
0
37
0
0
0
0
% N
% Pro:
0
0
19
37
28
10
10
10
10
19
19
0
0
10
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
19
0
0
0
10
0
0
37
0
10
0
10
37
% R
% Ser:
0
0
0
0
19
0
0
0
10
0
0
10
46
19
0
% S
% Thr:
37
0
10
10
0
0
19
10
0
10
0
0
0
0
0
% T
% Val:
0
0
37
0
19
0
46
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
37
0
10
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _